ncRNA name | CD46 siRNA |
ncRNA Category | siRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | immunohistochemistry, Western blot, siRNA transfection, ELISA |
Expression pattern | associated |
Functional description | CD46 knockdown increased release of VEGF on the apical and basal sides of ARPE-19 cells in culture by 1.3- (P = 0.012) and 1.2-fold (P = 0.017), respectively. |
PubMed ID | 26161984 |
Year | 2015 |
Title | Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium. |
Drug-related ncRNA | NO |
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